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SUP-B15(人急性淋巴細(xì)胞白血病)

CBP61164

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I. General information 
Synonyms: SUP-B15
Background: This line was was derived from malignant cells collected from the bone marrow of an 8 year old child with Philadelphia chromosome positive B cell ALL.
Species: Homo sapiens, human
Tissue: bone marrow
Disease: acute lymphoblastic leukemia
Gender: male,  8 years,  Caucasian
Morphology: lymphoblast
Growth Mode: suspension
Doubling Time: 18 hrs
DNA Profile: Amelogenin: X,Y
CSF1PO: 11,12
D13S317: 8,14
D16S539: 11,12
D5S818: 12,13
D7S820: 10,11
THO1: 6,9.3
TPOX: 8,9
vWA: 15,17
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Culture Medium:

IMDM+0.05 mM 2-mercaptoethanol+20%FBS

SUP-B15完全培養(yǎng)基,# CBP61164M
We strongly suggest to purchase the complete medium from us.

Cryopreservation medium: 90%FBS+10%DMSO
Antigen Expression: CD1a -; CD2 -; CD3 -; CD4 -; CD5 -; CD8 -; CD10 +; CD13 +; CD38 +; CD71 +; HLA DR +
Receptor Expression: N/A 
Karyotype N/A 
Virus Susceptibility N/A 
Oncogene: N/A 
Genes Expressed: immunoglobulin (cytoplasmic)
Cellular Products: immunoglobulin (cytoplasmic)
Tumor Formation: N/A 
Comments: The cells express multiple B lineage markers, but do not express T cell markers.
The cells are positive for the beta-2-microglobulin, Leu12, My7 (CD13), OKT9 (CD71), OKT10 (CD38) and CALLA (CD10) antigens.
They are are negative for CB1, Leu 1 (CD5), Leu2 (CD8), Leu3 (CD4), Leu4 (CD3), Leu5 (CD2), Leu6 (CD1a), Leu9, Leu M1 (CD15), My9 (CD33), surface immunoglobulin (sIg -) and Epstein-Barr virus.
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